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In severely iodine-deficient areas where iodized salt and daily iodine supplements are not available, the Iodine Global Network, the World Health Organization (WHO), and the United Nations Childrens Fund (UNICEF) recommend that lactating women receive a single annual dose of 400 mg of iodine (or 250 g/day) and exclusively breastfeed for at least six months

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Our analysis indicates that pathways related to energy metabolism (e.g., fatty acid metabolism, mitochondrial electron transport chain, TCA cycle) and amino acid metabolism (e.g., branched-chain amino acids, phenylalanine, tyrosine, and tryptophan) were particularly affected

Very high protein intakes, especially from mostly animal sources, may be a concern for people with kidney disease or certain cardiovascular risks, and long term excess can crowd out fiber rich foods