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The rubber stopper is an integral part of the vial's sterile barrier system and should never be removed

Men and women may yield different consequences based on dose, route, and biology

After starting and after each dose increase, tirzepatide can cut the peak absorption of an oral contraceptive by more than half, so the label guidance is a non-oral method or added barrier protection for four weeks after starting and four weeks after each increase. It is a first-dose-and-escalation effect, not a permanent block on all oral drugs

Hopefully you used the correct technique when giving yourself the injections, such as cleaning the top of the vial with a sterile alcohol wipe, and only using the alcohol wipe for one swipe across the top, and cleaning the skin where the injection will be given with a new sterile alcohol wipe, and only wiping the area once with each wipe

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