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Nbia Com cada vez mais opes surgindo no mercado, os medicamentos base de GLP-1 tm sido muito falados e usados por pessoas que buscam controle do diabetes tipo 2 e/ou reduo de peso
Retatrutide: The Triple Receptor Compound The compound at the center of this shift, retatrutide, hits three receptors at once: GLP-1, GIP, and glucagon
Key Points: GI symptoms are the most common adverse effects, ranging from expected nausea and vomiting to gastroparesis and, rarely, functional obstruction Delayed gastric emptying has important airway implications and a cautious approach to airway management is warranted Biliary disease is one of the most clinically significant complications, particularly early in treatment and with rapid weight loss Pancreatitis is rare, and current evidence does not support a strong causal relationship EDKA and AKI are uncommon but important to recognize in the right context Conclusions: GLP-1 receptor agonists have transformed the management of diabetes and obesity, with clear benefits in weight loss, glycemic control, and cardiovascular outcomes
In Retatrutide trials, 7% of participants stopped treatment due to side effects at the 12mg dose
Cureus 15(1):e33892
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