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An imbalance of glutathione is present in many pathologies including cancer, neurodegenerative disorders, cystic fibrosis (CF), HIV and aging

Its three-dimensional structure also comprises a predominant Rossmann-fold domain that is largely conserved, with a secondary domain including a zinc-binding module as well as a helical module

N-A-C is routinely used in hospitals as an antidote to the pain reliever acetaminophen, particularly when ingested with alcohol, or taken in excessive amounts

In vitro and in vivo antitumour activities of puerarin 6-O-xyloside on human lung carcinoma A549 cell line via the induction of the mitochondria-mediated apoptosis pathway

On one hand, neutrophils significantly contribute to immune dysregulation and tissue damage through the formation of neutrophil extracellular traps (NETs), which are rich in decondensed nucleic acids and expel chromatin that can trigger specific autoreactive immune responses to nucleic acid antigens (79, 80)