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Adems, en algunos se tenan en cuenta otras variables clnicas, como la ganancia ponderal o la apnea

The DOX/LAAM GSH-CQDs accumulated in the tumor within 30 min and lasted for 24 h, and the fluorescence intensities in the DOX/LAAM GSH-CQDs were two to three times higher than those found for free DOX in the tumors (Supplementary Fig

Molecular signaling in adipose tissue research models

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This function is mediated via the activation of the cAMP/PKA/CREB (cAMP-responsive element binding protein) and the transactivation of the EGF-R (epidermal growth factor receptor) leading to the activation of phosphatidylinositol-3 kinase (PI3K), protein kinase C(PKC), Akt-protein kinase B (AKT/PKB), extracellular regulated kinase (ERK1/2 or mitogen-activated protein kinase [MAPK]) signaling pathways and to the up-regulation of the expression of the cell cycle regulator cyclinD1 (Figure 3)