Simulation set-up The MD simulations of wild-type p97-ND1L in the ADPP i state and point mutations thereof (N348Q, R359K, F360P) were started from the crystal structure with PDB 4KO8 (ref
International Journal of Pediatric Obesity , 8(4), 273-282
Common results: According to authors Rodriguez et al., most achieved weight loss of 5% or greater. However, the authors also noted that the benefit was greater with tirzepatide
In common with other agents in the GLP-1 receptor agonist class, there is a potential risk of acute pancreatitis and gallbladder disease (including gallstones and cholecystitis)
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